Sudden infant death syndrome and cardiac channelopathies: from mechanisms to prevention of avoidable tragedies

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Cardiac Ion Channelopathies and the Sudden Infant Death Syndrome

The sudden infant death syndrome (SIDS) causes the sudden death of an apparently healthy infant, which remains unexplained despite a thorough investigation, including the performance of a complete autopsy. The triple risk model for the pathogenesis of SIDS points to the coincidence of a vulnerable infant, a critical developmental period, and an exogenous stressor. Primary electrical diseases of...

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Sudden infant death has haunted humanity since Biblical times, and many people are still confused about how to differentiate sudden infant death syndrome from other causes of sudden infant death, such as myocarditis or congenital heart disease. Because of the difficulty of diagnosis, the authors say that SIDS has become a “diagnostic dustbin,” but unnecessarily so. They provide the diagnostic c...

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Sudden cardiac death poses a unique challenge to clinicians because it may be the only symptom of an inherited heart condition. Indeed, inherited heart diseases can cause sudden cardiac death in older and younger individuals. Two groups of familial diseases are responsible for sudden cardiac death: cardiomyopathies (mainly hypertrophic cardiomyopathy, dilated cardiomyopathy, and arrhythmogenic ...

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ژورنال

عنوان ژورنال: Cardiogenetics

سال: 2011

ISSN: 2035-8148,2035-8253

DOI: 10.4081/cardiogenetics.2011.s1.e6